Another hour goes by and another cup of coffee is poured. But, how much is healthy?
Can you die from drinking too much caffeine? Caffeine, a central nervous stimulant, is arguably the most ingested pharmacologically active substance in the world.
Caffeine has an LD50 dose in rats (the dose necessary to kill half of the test rats) of 192 milligrams per kilogram.
Extrapolating this into the human population, 12 grams of caffeine would be lethal for a 60 kilo adult.
“This amount of caffeine is contained in 118 cups of coffee. So, yes, caffeine can literally be lethal, but would require consuming a massive quantity of coffee” – (Guy Crosby – America’s Test Kitchen, Science Editor).
Other experts wade into the discussion with what are both acceptable or not.
For healthy adults, FDA has cited 400 milligrams a day—that’s about four or five cups of coffee—as an amount not generally associated with dangerous, negative effects. The Academy of Paediatrics discourages caffeine consumption in children and adolescents – (Theresa Eisenman, FDA)